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Rock Street, San Francisco
Rock Street, San Francisco
Question Answer
cholinergic-blocking drugs drugs that block the action of acetylcholine and substances similar to acetylcholine at receptor sites in the brain
mydriasis dilation of the pupil of the eye cause by contraction of the dilator muscle of the iris
parasympatholytics drugs that reduce the activity for he parasympathetic nervous system; also called anticholinergics
cholinergic blockers, anticholinergics, parasympatholytics and antimuscarinic drugs are all terms that refer to the calsss of drugs that block or inhibit he actions of acetylcholine in the parasympathetic nervous system
cholinergic blocking drug action they block the action of the neurotransmitter acetylcholine at the muscarinic receptors in the parasympathetic nervous system
blocking the parasympathetic nervous system allows the sympathetic (adrenergic) nervous system to dominate
cholinergic are largely competitive antagonists – as they compete with acetylcholine for binding at the muscarinic receptors of the parasympathetic nervous system
cholinergic blockers have little effect at the nicotinic receptors, although at high does that can have partial blocking effects there
the major sites of action of the cholinergic- blocking drugs are the heart, respiratory tract, GI tract, urinary bladder, eye, and exocrine glands (sweat gland, salivary gland)
anticholinergic effects on the cardiovascular system are seen as an increase in heart rate
anticholinergic effects on the respiratory system are dry mucous membranes and bronchial dilation
in the GI tract anticholinergics cause a decrease in GI motility, GI secretions, and salivation
In GU systems anticholinergics lead to decreased bladder contraction which can result in urinary retention
in the skin anticholinergics reduce sweating
anticholinergics casue ______ in the eye increase intraocular pressure and cause the pupils to dilate
in the CNS cholinergic blockers have the therapeutic effects of decreasing muscle rigidity and diminishing tremors, this is beneficial in the treatment of both Parkinson's disease and extrapyramidal reactions
at low dosages anticholinergics effects on cardiovascular system slow hear rate through their effects on the cardiac centre in the medulla
at high dosages cholinergic blockers block ______in cardiovascular system the inhibitory vagal effects on the pacemaker cells of the SA and AB nodes which leads to accelerated hear rate because of unopposed sympathetic act
Atropine is used primarily in the management of cardiovascular disorders such as in the diagnosis of the sinus node dysfunction, AB block and provisions of life support treatment
when cholinergic stimulation of the parasympathetic NS is blocked by cholinergic blockers the SNS effects fo unopposed, in the rest tract this results in decreased secretions from the nose, mouth, pharynx, and bronchi
anticholinrgics have been proved to be beneficial in treating exercise induced bronchospasm, asthma, and COPD
anticholinergics are also ysed preoperatively to reduce salivary secretions which aids in intubating and other procedures involving the oral cavity
anticholinergics are useful in the treatment of GU tract disorders such as reflex neurogenic bladder and incontinence.
anticholinergic drugs are contraindicated in known drug allergy, angle – closure glaucoma, acute asthma or other respiratory distress, myasthenia grabs, acute cardiovascular instability
ADE of anticholinergic drugs – people that are more susceptible infants, children with down syndrome, spastic paralysis or brain damage, older adults – cognitive impairment and delierium
the dose of cholinergic blockers is important becahyse there is a small difference between therapeutic and toxic dosages. – low therapeutic index
drug interactions include additive effects with drugs such as amantadine hydrochloride, antihistamines, and TCA
cholinergic blockers are used in the treatment of a variety of illnesses and conditions – irritable bowel syndrome, to symptoms of a common cold, administered preoperatively
atropine sulphate classification naturally occurring antimuscarinic and it used for its cholinergic blocking effects on the heart and effects smooth muscle of bronchi and intestines
atropine is used to treat bradycardia and ventricular systole – also antidote for anti cholinesterase inhibitor toxicity or poisoning
dicyclomine hydrochloride classification synthetic antispasmodic cholinergic blocker used for treatment primarily for functional disturbances of GI – irritable bowel and spastic constipation
glycopyrrolate classification synthetic antimuscarinic drug that blocks receptor sites in the ANS controlling the production of secretions and the concentration of free fatty a
glycopyrrolate is used preoperatively – contraindicated in patients who are hypertensive and in those with angle closure glaucoma, myasthenia grabs, GI and GI obstruction
oxybitynin chloride classification and use synthetic antimuscarinic drug used for the treatment of overactive bladder, and as antispasmodic for neurogenic pbladder associated with spinal cord in
scopolamine hydrobromide classification naturally occurring cholinergic blocker – principal belladonna alkaloids – most potent antimuscarinic for prevention of motion sickness
tolterodine tartrate classification muscarinic receptor blocker used for the treatment of urinary frequency, urgency, and urge incontinance cause by bladder overactivity
before giving an anticholinergic drug the nurse should check the patients history for which conditions glaucoma, acute asthma, benign prostatic hyperplasia
ADE to expect from the anticholinergic drugs include dilated pupils, dry mouth, urinary retention
in reviewing the med orders the nurse recognizes that atropine sulphate is an indication for which condition reduction of secretions preoperatively
during patient teaching a 70 yr old, taking anticholinergic drug, the nuse should reinforce the point that this med places patient at hight risk for? heat stroke
28yr old patient prepping for a cruise asked for med for motion sickness what must nurse say to this patent about proper use of patches apply the patch 4-5 hours before travel
patient has new prescription for tolterodine L-tartrate. Which condition if present would make it necessary to reduce the usual dose of drug cirrhosis of the liver

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